[HTML][HTML] Oxidative stress and the neurovascular unit

C Rinaldi, L Donato, S Alibrandi, C Scimone… - Life, 2021 - mdpi.com
… the VEGF transcriptional level in the brain endothelial cells exposed to oxidative stress or
thrombin [… Instead, lithium accumulation or overdose reduces endothelium-dependent but not …

[HTML][HTML] The mechanism of ferroptosis regulating oxidative stress in ischemic stroke and the regulation mechanism of natural pharmacological active components

K Yang, L Zeng, X Yuan, S Wang, A Ge, H Xu… - Biomedicine & …, 2022 - Elsevier
… each neurovascular unit during post-stroke hypoxia and reperfusion play an important role
… the pathological process of ferroptosis in the neurovascular unit of acute stroke. Some drugs …

Differential Vulnerability and Response to Injury Among Brain Cell Types Comprising the Neurovascular Unit

P Rajput, A Brookshier, S Kothari… - Journal of …, 2024 - Soc Neuroscience
… involved 291 with hypoxia, oxidative stress, neuronal toxicity and PAR-1 … thrombin injury
without showing a dose response effect across the doses we 383 tested, suggesting thrombin

[HTML][HTML] The relationship between amyloid-beta and brain capillary endothelial cells in Alzheimer's disease

YL Zhang, J Wang, ZN Zhang, Q Su… - Neural Regeneration …, 2022 - journals.lww.com
… cerebrovascular effects by promoting oxidative stress, … changes in the neurovascular units
constituting the BBB contribute … VEGF-stimulated endothelial nitric oxide synthase and VEGF-…

Neuroprotective and neurorestorative effects of Epo and VEGF: perspectives for new therapeutic approaches to neurological diseases

ME Ureña-Guerrero… - Current …, 2020 - ingentaconnect.com
… of neuroprotection is protecting the neurovascular unit (NVU), … effects without inducing
toxic side effects, this has not yet … counteracts the deleterious effects of oxidative stress [151]. …

[HTML][HTML] The neurovascular unit dysfunction in Alzheimer's disease

LO Soto-Rojas, M Pacheco-Herrero… - International Journal of …, 2021 - mdpi.com
… of blood-derived proteins (thrombin, fibrinogen, plasminogen, … and neuroprotective effects,
such as regulation of oxidative stress and increasing … VEGF Vascular endothelial growth factor …

Patching up the permeability: the role of stem cells in lessening neurovascular damage in amyotrophic lateral sclerosis

M Monsour, S Garbuzova-Davis… - Stem Cells …, 2022 - academic.oup.com
… This review elucidates the role of the neurovascular unit in … hypoxia response element in
the VEGF gene promotor blocks … These patients also had increased IgG, fibrin, and thrombin in …

[HTML][HTML] Oxidative stress, reductive stress and antioxidants in vascular pathogenesis and aging

M Mladenov, L Lubomirov, O Grisk, D Avtanski… - Antioxidants, 2023 - mdpi.com
effect of ROS accumulation on the neurovascular unit is … growth factor (VEGF), thus having
pleiotropic effects on a variety of … at high doses of up to 12 g/day [155], while toxicity studies in …

Blood-brain Barrier and Neurovascular Unit Dysfunction in Parkinson's Disease: From Clinical Insights to Pathogenic Mechanisms and Novel Therapeutic Approaches

SLQ Khor, KY Ng, RY Koh… - CNS & Neurological …, 2024 - ingentaconnect.com
… endothelial growth factor (VEGF) and Notch homolog protein … mitochondrial dysfunction and
increased oxidative stress [36]. … RhoA by thrombin in endothelial hyperpermeability: Role of …

Lost in translation: Neurotrophins biology and function in the neurovascular unit

G Mirzahosseini, JM Adam, S Nasoohi… - The …, 2023 - journals.sagepub.com
… Our group has discovered that diabetes-associated oxidative stress … factor (VEGF). Despite
the great strides in developing anti-… In conclusion, further experiments using different doses of …